What is Duchenne Muscular Dystrophy?: Background information when reading The Revised Fundamentals of Caregiving

Summary |  Excerpt |  Reviews |  Beyond the Book |  Readalikes |  Genres & Themes |  Author Bio

The Revised Fundamentals of Caregiving

A Novel

by Jonathan Evison

The Revised Fundamentals of Caregiving by Jonathan Evison X
The Revised Fundamentals of Caregiving by Jonathan Evison
  • Critics' Opinion:

    Readers' Opinion:

  • First Published:
    Aug 2012, 288 pages
    Paperback:
    May 2013, 304 pages

  • Rate this book


Book Reviewed by:
Judy Krueger
Buy This Book

About this Book

What is Duchenne Muscular Dystrophy?

This article relates to The Revised Fundamentals of Caregiving

Print Review

Muscular Dystrophy encompasses a a group of usually inherited disorders that involve increasing muscle weakness and loss of muscle tissue over time. Duchenne muscular dystrophy (DMD) is a rapidly worsening form of the disorder that affects only males. The usual cause is a defective gene carried by the mother, but about one-third of cases appear to be spontaneous mutations in the male's genes. Many mutations of the gene can cause DMD but only some common ones have been identified. Symptoms of DMD, which include fatigue, learning difficulties, muscle weakness and progressive difficulty walking, usually appear early in life around age 5.

DMD's gene inheritance map Diagnosis is primarily accomplished by DNA testing though a muscle biopsy test is sometimes required. If a pregnant woman has the genetic mutation that causes the disease, there is a 50% chance that a female child will inherit that mutation and that a male child will have DMD. Prenatal tests can determine if the fetus has one of the most common mutations that cause DMD.

Many sufferers lose the ability to walk by age 12 and spend the remainder of their lives in a wheelchair. Muscular deterioration leads to breathing difficulties and heart disease. The chest and back become deformed and the muscles of the extremities gradually contract.

Treatment includes respirators, drugs to assist heart function, and steroid drugs to slow the loss of muscle strength, but currently there is no known cure and death by age 25 is typical.

Caring for a DMD patient involves administering medications, supervising diet, assisting with elimination, moving him from bed to wheelchair and back, dressing him, and ensuring proper use of respiratory support as the disease progresses.

Medical research into DNA and drugs, physical therapy and daily patient care have improved the quality and even the duration of life for DMD sufferers. Researchers are also investigating the use of stem cell replacement and gene therapy to repair the muscular damage caused by genetic mutation. It remains to be seen if these approaches could result in a cure.

Picture from Muscular Dystrophy Association

This "beyond the book article" relates to The Revised Fundamentals of Caregiving. It originally ran in September 2012 and has been updated for the May 2013 paperback edition.

This review is available to non-members for a limited time. For full access become a member today.
Membership Advantages
  • Reviews
  • "Beyond the Book" backstories
  • Free books to read and review (US only)
  • Find books by time period, setting & theme
  • Read-alike suggestions by book and author
  • Book club discussions
  • and much more!
  • Just $10 for 3 months or $35 for a year
  • More about membership!

Editor's Choice

  • Book Jacket: In Byron's Wake
    In Byron's Wake
    by Miranda Seymour
    It's tempting to think that our age of celebrity worship coupled with the 24-hour news cycle is ...
  • Book Jacket: The Latecomers
    The Latecomers
    by Helen Klein Ross
    The Latecomers is the third novel written by acclaimed author Helen Klein Ross, following What Was ...
  • Book Jacket: The Inflamed Mind
    The Inflamed Mind
    by Edward Bullmore
    It is common knowledge that depression diminishes the quality of sufferers' lives, but few people ...
  • Book Jacket: The Adults
    The Adults
    by Caroline Hulse
    Things have already fallen apart on the first page of The Adults. The novel opens with an emergency ...

Book Discussion
Book Jacket
Becoming
by Michelle Obama

An intimate, powerful, and inspiring memoir by the former First Lady of the United States.

About the book
Join the discussion!

Readers Recommend

  • Book Jacket

    House of Stone
    by Novuyo Rosa Tshuma

    A masterful debut, pulsing with dark humor, that explores the often destructive act of history-making.
    Reader Reviews

Win this book!
Win Uncommon Type

Uncommon Type
by Tom Hanks

Surprising, intelligent, heartwarming, and a must-have for Tom Hanks fans!

Enter

Word Play

Solve this clue:

Tell I T T M

and be entered to win..

Books that     
entertain,
     engage

 & enlighten

Visitors can view some of BookBrowse for free. Full access is for members only.

Join Today!

Your guide toexceptional          books

BookBrowse seeks out and recommends books that we believe to be best in class. Books that will whisk you to faraway places and times, that will expand your mind and challenge you -- the kinds of books you just can't wait to tell your friends about.