The Disordered Mind: Book summary and reviews of The Disordered Mind by Eric R. Kandel

The Disordered Mind

What Unusual Brains Tell Us About Ourselves

by Eric R. Kandel

The Disordered Mind by Eric R. Kandel X
The Disordered Mind by Eric R. Kandel

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Book Summary

Nobel Prize recipient Eric R. Kandel investigates The Disordered Mind to uncover what brain disorders reveal about human nature.

Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts.

In his seminal new book, The Disordered Mind, Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain? The brain's 86 billion neurons communicate with one another through very precise connections. But sometimes those connections are disrupted. As a result, the brain processes that give rise to our mind can become disordered, resulting in diseases such as autism, depression, schizophrenia, Parkinson's, addiction, and post-traumatic stress disorder. While these disruptions bring great suffering, they can also reveal the mysteries of how the brain produces our most fundamental experiences and capabilities - the very nature of what it means to be human. Studies of autism illuminate the neurological foundations of our social instincts; research into depression offers important insights on emotions and the integrity of the self; and paradigm-shifting work on addiction has led to a new understanding of the relationship between pleasure and willpower.

By studying disruptions to typical brain functioning and exploring their potential treatments, we will deepen our understanding of thought, feeling, behavior, memory, and creativity. Only then can we grapple with the big question of how billions of neurons generate consciousness itself.

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Reviews

Media Reviews

"Starred Review. [An] easily comprehended, meticulous synthesis of current research into the biological grounding of the human mind." - Publishers Weekly

"Synaptic pruning, folded proteins, adaptive habits: all fascinating stuff ably interpreted by a master." - Kirkus

"Kandel's clear and straightforward writing makes this informative scientific exploration accessible and compelling to both medical practitioners, researchers, and general readers interested in how the mysteries of human nature arise from the physical matter of the brain." - Library Journal

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Author Information

Eric R. Kandel

Eric R. Kandel is a University Professor and Fred Kavli Professor at Columbia University and a Senior Investigator at the Howard Hughes Medical Institute. The recipient of the 2000 Nobel Prize in Physiology or Medicine for his studies of learning and memory, he is the author of In Search of Memory, a memoir that won a Los Angeles Times Book Prize; The Age of Insight: The Quest to Understand the Unconscious in Art, Mind, and Brain, from Vienna 1900 to the Present, which won the Bruno Kreisky Award in Literature, Austria's highest literary award; and Reductionism in Art and Brain Science: Bridging the Two Cultures, a book about the New York School of abstract art. He is also the coauthor of Principles of Neural Science, the standard textbook in the field.

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