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Mercies in Disguise Reading Guide & Discussion Questions

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Mercies in Disguise by Gina Kolata

Mercies in Disguise

A Story of Hope, a Family's Genetic Destiny, and the Science That Rescued Them

by Gina Kolata
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  • Critics' Consensus (4):
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  • First Published:
  • Mar 21, 2017, 272 pages
  • Paperback:
  • Apr 2018, 272 pages
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Book Club Discussion Questions

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For supplemental discussion material see our Beyond the Book article, Genetic Testing and our BookBrowse Review of Mercies in Disguise.


Please be aware that this discussion guide will contain spoilers!

  1. What is the meaning of the title, Mercies in Disguise? What mercies are apparent for the family members? Do the family members see different mercies?
  2. If you knew that you were at risk for a fatal genetic condition that had no cure, would you want to be tested for the genetic mutation? Why or why not? What if the person at risk were your child? Your spouse?
  3. Why do you think the history of the Fore in New Guinea was included? How did the discovery of Kuru lay a foundation for discoveries about GSS and other prion diseases?
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  1. How does the author develop themes of identity and belonging throughout the narrative?
  2. What role does the setting play in shaping the characters' decisions and relationships?
  3. Discuss how the ending reframes the events of the story. Were you surprised?


Unless otherwise stated, this discussion guide is reprinted with the permission of St. Martin's Griffin. Any page references refer to a USA edition of the book, usually the trade paperback version, and may vary in other editions.

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Beyond the Book:
  Genetic Testing

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