What is Duchenne Muscular Dystrophy?: Background information when reading The Revised Fundamentals of Caregiving

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The Revised Fundamentals of Caregiving

A Novel

by Jonathan Evison

The Revised Fundamentals of Caregiving
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  • First Published:
    Aug 2012, 288 pages
    May 2013, 304 pages

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Book Reviewed by:
Judy Krueger

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Beyond the Book:
What is Duchenne Muscular Dystrophy?

Muscular Dystrophy encompasses a a group of usually inherited disorders that involve increasing muscle weakness and loss of muscle tissue over time. Duchenne muscular dystrophy (DMD) is a rapidly worsening form of the disorder that affects only males. The usual cause is a defective gene carried by the mother, but about one-third of cases appear to be spontaneous mutations in the male's genes. Many mutations of the gene can cause DMD but only some common ones have been identified. Symptoms of DMD, which include fatigue, learning difficulties, muscle weakness and progressive difficulty walking, usually appear early in life around age 5.

DMD's gene inheritance map Diagnosis is primarily accomplished by DNA testing though a muscle biopsy test is sometimes required. If a pregnant woman has the genetic mutation that causes the disease, there is a 50% chance that a female child will inherit that mutation and that a male child will have DMD. Prenatal tests can determine if the fetus has one of the most common ...

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