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My Sister's Keeper Reading Guide & Discussion Questions

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My Sister's Keeper by Jodi Picoult

My Sister's Keeper

by Jodi Picoult
  • Critics' Consensus (9):
  • Readers' Rating (99):
  • First Published:
  • Apr 1, 2004, 423 pages
  • Paperback:
  • Feb 2005, 448 pages
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Book Club Discussion Questions

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For supplemental discussion material see our Beyond the Book article, and our BookBrowse Review of My Sister's Keeper.


Please be aware that this discussion guide will contain spoilers!

  1. One of this novel's strengths is the way it skillfully demonstrates the subjectivity people bring to their interactions with others. The motivations of individual characters, the emotions that pull them one way or another, and the personal feelings that they inject into professional situations becomes achingly clear as we explore many different viewpoints. For example, despite Julia and Campbell's attempts to remain calm, unemotional and businesslike when they deal with one another, the past keeps seeping in, clouding their interaction. The same goes for the interaction between Sara and Anna during the trial. Is there such a thing as an objective decision in the world of this story? Is anyone capable of being totally rational, or do emotions always come into play?
  2. What do you think of this story's representation of the justice system? What was your opinion of the final outcome of the trial?
  3. What is your opinion of Sara? With her life focused on saving Kate, she sometimes neglects her other children. Jesse is rapidly becoming a juvenile delinquent, and Anna is invisible -- a fact that the little girl knows only too well. What does this say about Sara's role as a mother? What would you have done in her shoes? Has she unwittingly forgotten Jesse and Anna, or do you think she has consciously chosen to neglect them -- either as an attempt to save a little energy for herself, or as some kind of punishment? Does Sara resent her other children for being healthy? Did you find yourself criticizing Sara, empathizing with her, or both?
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  1. How does the author develop themes of identity and belonging throughout the narrative?
  2. What role does the setting play in shaping the characters' decisions and relationships?
  3. Discuss how the ending reframes the events of the story. Were you surprised?


Unless otherwise stated, this discussion guide is reprinted with the permission of Washington Square Press. Any page references refer to a USA edition of the book, usually the trade paperback version, and may vary in other editions.

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